Lithium and Inositol had been such a great help, with recovery of 2 years of hard substances abuse, I feel relatively normal again, with a much better quality of life, and lots of motivation and happiness. Some of the people on Reddit and Longecity claim benefits from using lithium orotate so the anecdotal data seems to be in favor. I would like your opinion if I can remove 1 or 2 adaptogens from my morning stack (may be 4 of them work in the simular way, and there’s no need to keep 4 of them). Another common mutation that is found in people with anxiety, ADD/ADHD, and/or insomnia is on the COMT gene. But I found one website that said is was not. Hi saw your post about lithium and inositol. When I read about Lithium Orotate I was very impressed & did a followup research. how did adding inositol impact the lithium effects? https://selfhacked.com/blog/5ht2a-receptors-a-root-cause-of-anxiety-fatigue-sleep-problems-and-cirs/. The amount you need orally can vary a lot though, 2000 - 10000iu. 5000 is a safe starting place. If so, what were the effects? Lithium orotate has received only minimal evaluation in terms of its safety. I will take 450mg Ashwagandha in the morning, 450mb at dinner, 5mg Lithium Oratate about an hour before bed and Calcium Magnezium Zink right before bed. Some clinical studies shows that lithium orotate may lower impulsive-aggressive behaviors linked to ADHD. Call your doctor for medical insight concerning side impacts. I noticed many of these countless side effects that only get worse when I smoke cannabis or Utilize agmantine. Lithium is present in the diet, mainly in grains and vegetables, which is why the supplement is often called “nutritional lithium.” Agmantine may activate the 5HT2A receptors. Did you start taking those simultanesly? Did the lithium dampen or nullify the effectiveness of your amphetamine dose, smooth it out, or synergize in some beneficial way? Intense overwhelming fear states .... Bad trips .... Intense activation of the stress and fear centres of the brain which similarly but inversely can have long lasting negative phsycological effects that are basically the equivalent to PTSD. The reason being is because Lithium Orotate is bonded with orotic acid. Lithium in any form at that dosage is not a dietary supplement; it is a drug which has serious side effects. I have been taking Lithium Oratate 5mg once a day and felt as if it was making the difference but didn't want to depend on it. Lithium orotate is an over-the-counter nutraceutical that consists of orotic acid (a compound produced naturally in the body) and lithium (an alkali metal). From novel/alternative substances, to established medications. That is true, if not for the statement in the abstract that ketanserin attenuated the reduction in glutathione. As far as cosmologists can tell, there were only three elements present when the universe was first formed some 13.8 billion years ago: hydrogen, helium, and lithium. This only applies to lithium carbonate, the commonly prescribed form. Do not use desvenlafaxine within 14 days of quiting an MAOI meant to treat psychological conditions. Some of the nootropics that I want to add to treat TBI like Lithium Orotate can also treat social anxiety. So how this article describes it, is that Lithium inhibits GSK3b which can help fix these receptors. It really seemed to change after she started the Inositol. Many patients go off of their Li carbonate in favor of a small dose of freely-purchasable-online Li orotate which they say works better. simple chemical salt – just like lithium carbonate or lithium citrate Ashwagandha and magnesium are both safe and healthy. Usually they have a good rating and reputation. However, scientists recommended that lithium prescription should only be given after other drugs have failed to work. A nootropic is a substance that enhances cognition and memory and facilitates learning.. Neuro-hacking and the research behind brain modulation, nootropics, and bio-hacking in general is a constantly evolving and improving science. NOW Adam Multi Vitamin For Men Now Ashwagandha 450mg Now Zinc 50mg Sports Research Vitamin D3 5000 Amazing Herbs Black Cumin Seed Oil Solaray Calcium Mag Zinc KAL Lithium Oratate 5mg Reishi Mashroom Powder Orgain Plant Based Protein Shilajit Collagen Peptides BCAA Amino Energy Pre Workout Magnesium Calm, but run out of it, More posts from the depressionregimens community, Continue browsing in r/depressionregimens. Most websites claimed it was safe in small doses. Inositol + Lithium would be a good stack to mount, if you're interested in these effects. Biochemical effects - both good and bad are dramatically increased. This sub is not for venting or for facebook style posts. Very calming but can’t take it everyday because it makes me sleepy.” Some clinical studies shows that lithium orotate may lower impulsive-aggressive behaviors linked to ADHD. Pleasure centres of the brain and those associated with social connection are activated in ways not ordinarily possible bring out experience that can actually alter people's outlook and experience of life forever - often in very positive ways (though not always viewed that way in today's western capitalistic materialistic culture). Lithium Orotate Reddit Reviews Definitely makes negative thought processes in my mind go from autonomous parasites ruminating, to something that actively takes effort, making perception related depression more of a choice. But take them in stressful, angry, chaotic environment .... You can get the opposite. The limited research out there on lithium orotate shows that it raises blood levels just as much as lithium carbonate, a prescription medication which often causes blood toxicity. And i cycle through 5 days on 2 days off every week just to keep my lithium levels on check. I believe you’re on to something here and some of these thoughts have been in my mind about the 5ht2a and it’s constant change from illicit and natural substances and it’s overt influence on our experience of life. So take them in a peaceful, fun environment with positive people you are friends with and you can have profoundly uplifting, loving - even spiritual divine experiences. Over-the-counter lithium orotate is promoted as a health supplement for use as a low-dose source of lithium. Reddit. This basically sums it up, not to say that I take it all at once or regular bases. Although Lithium decreases brain inositol levels, it is worth noting that if you decide to utilize inositol, it may also help by reducing the function of 5HT2A at the receptor-G protein level . Lithium orotate ADHD. Lithium Orotate; Lithium is an alkali mineral considered essential for human reproductive health, and general health and wellness. I've never once heard of lithium orotate as a treatment for ADHD or sensory processing disorder symptoms. Both good and bad. Please see my post, you are speaking in ignorance. Anyone tried Lithium Orotate with Adderall/Dexedrine? Some consider it an alternative to Lithium Carbonate, but the evidence in this sense is controversial. On earth, lithium remains a major mineral component of granite rock, and also lingers in significant amounts in sea water, mineral springs, and soils. "Furthermore, MDMA depleted intracellular glutathione (GSH) levels in a concentration dependent manner, an effect that was attenuated by Ketanserin, a competitive 5-HT(2A)-receptor antagonist."https://www.ncbi.nlm.nih.gov/pubmed/17572501. The limited research out there on lithium orotate shows that it raises blood levels just as much as lithium carbonate, New comments cannot be posted and votes cannot be cast, Most of my supplements are from NOW brand. Please do not use it daily without medical supervision. Make sure you take a fairly high dose of magnesium with it (don't use crap versions like chloride or oxide either. But we felt we should follow through with the recommendation. Smith That study seems to have brought an end to scientific study of the orotate approach. Evening: Lithium Orotate 4mg (liquid) Inositol 750mg Vitamin D liquid 1000IU Magnesium 200mg Niacin 500mg. I probably wouldn’t buy lithium orotate by itself, though. Other treatment modalities are welcome as long as there is a clear intention towards symptom improvement, and at least a modest attempt at being scientific. Even though I do feel the difference, today I had an episode of anxiety. Google for the difference as it's really important. However, scientists recommended that lithium prescription should only be given after other drugs have failed to work. The lithium is an all natural mineral (not the prescription strength drug) and she'd be on the lowest dose. Advanced Research Lithium Orotate, for example, contains 120 mg of lithium orotate, but 4.6 mg of elemental lithium. But the good goes a long way apparently enhancing dopamine in areas responsible for a higher level thinking, which is the main mechanism of LSD, to my understanding. Lithium orotate weight loss. Lithium orotate is a safe, well tolerated, and well absorbed dietary source of lithium. Orotate occurs naturally in our diet and is also routinely made in the body. As one of the three original elements, lithium is found throughout our atmosphere. Lithium asparate is supposedly safer for regular use. Although lithium orotate is considered safer than other lithium-based compounds, there are still a number of side effects, drug interactions and potentially serious conditions that can result from regular lithium orotate use 1 3. My daughter had many of the same things as yours (sensory, rages, moody, attention problems and anxiety). Discussion and anecdotes are welcome! On thing that helps somewhat is lithium oratate, not sure what would i do if i stop taking it, or take it only once a week. Supplementing with lithium does not change your state of consciousness. Microdosing lithium using Lithium Orotate has become one of the best additions I’ve made to my nootropic stack in years. I am out of a 10 year relationship with a narcissist, and still suffering the consequences. These conditions include Alzheimer's and dementia patients, ADD and ADHD, and violent and aggressive behaviors. The recommended daily allowance (RDA) of lithium is 1 mg/dayMarshall 2015; supplemental lithium orotate doses up to 20 mg/day have been suggested.Marshall 2015 However, adequate clinical studies are lacking to support dosage recommendations. How to you take lithium orotate and inositol? Press question mark to learn the rest of the keyboard shortcuts. If activation of these receptors causes anxiety, ocd, etc. The limited research out there on lithium orotate shows that it raises blood levels just as much as lithium carbonate, a prescription medication which often causes blood toxicity. I am also on Keto Diet which is high sodium/potassium/magnesium due to it being diuretic by nature (diet has helped my mental health immensely) - does Lithium Oratate dehydrate you or mess with your electrolytes? A confirmed mutagen that can cause cancer. Personally I would not recommend your choice of magnesium supplement - magnesium calcium and zinc are absorbed through the same channel and hinder each other's absorbtion. Where have you read they lithium asparate is safer than lithium orotate? Lithium orotate — known by the names lithium carbonate, lithium citrate and simply lithium — is a compound used to treat a number of neurological conditions 1. Im wondering if any of my fellow canadians ever managed to order some and receive the package safely. This kind of complicated to understand. Any suggestions? One 1979 study in rats found it more harmful than the conventional form (lithium carbonate) to the animals’ kidneys. Lithium orotates did solve my rumination and circular thoughts which was a huge problem for me but it kinda makes me kinda numb at times, it would be great if inositol can help. Lithium has been shown in studies to calm manic behavior associated with anxiety, bipolar disorder, and even attention deficit disorder (ADHD). Lithium is most famous for its antipsychotic effects in bipolar patients. The orotate doesn't have this danger as it's active at just 5mg of elemental lithium. New comments cannot be posted and votes cannot be cast. Lithium has also found its w… The more receptors we have, the more likely they’ll activate, so it’s better to have fewer receptors. Lithium Orotate 4mg (liquid) Inositol 1500mg 2 MedPro pills Niacin 500mg B-12/Folic Acid/B-6. Hi, Does Lithium Orotate (5-20mg/day) mess with your kidney and thyroid like carbonate? Vitamin D is also a must for most people. Been thinking of trying inositol, have been on lithium orotate around 7 months, has helped with my suicidal thoughts but no motivation. Inositol + Lithium would be a good stack to mount, if you're interested in these effects. Benefits of Lithium Orotate I feel pretty much the exact opposite of every single symptom listed for that while on it. The sun, stars, and meteorites burn brightly with the flame of this highly reactive element. If you follow the links in the article a lot of these studies don't say what the author thinks they say. It simply helps bring you back to feeling normal and happy. https://journals.sagepub.com/doi/10.1177/0269881117725915. It is either due to previous stress or a nerve damage, but I have a racing mind, where I either keep spinning the same thought over and over or about 10 seconds of the last song i hear keeps being repeated in my mind non stop. In a study published in the Journal of Affective Disorders and conducted by Dr. Linda Franchini et al., lithium orotate was one of the potential outpatient treatments for mood disorders. Click here to learn more about Lithium Orotate. It proposes that the principal function of brain serotonin is to enhance adaptive responses to adverse conditions via two distinct pathways: (1) a passive coping pathway which improves stress tolerability; and (2) an active coping pathway associated with heightened plasticity, which, with support, can improve an organism’s ability to identify and overcome source(s) of stress by changing outlook and/or behaviour. what does it mean for me if LSD instantly stops all anxiety/depression for me? Studies have determined that giving lithium to dementia patients. Lithium metal is in the drinking water of many cities, and there is a correlation of lowered incidences of crimes, suicides, and arrests related to drug addictions in these areas. Because of these mood-stabilizing effects, lower lithium dosage are being explored in people with anxiety. So Emma had to … Personally I take zinc in the morning and magnesium at night. Lithium Orotate is a chemical compound of orotic acid and lithium, used to treat mental conditions such as bipolar disorder, Alzheimer’s disease, alcoholism or ADHD. I read a really interesting article on the serotonigenic system recently, highlighting in particular the 5-HT1A and 5-HT2A systems in the brain and what we know so far (as of 2017). Its not a fixed effect - but rather a multiplier of whatever the the individual is feeling while taking it. Genuinely curious because I take lithium orotate regularly. Citrate glycinate malate are solid, magnesium l-threonate is the best for the brain but its expensive and you need to take another form with it to adequately raise levels across the whole body. This is why those who studied them medicinally in the 60s and 70s emphasised 1 critic thing that determined how they effected people: Set and setting. Al-Quds University. Discussion of nootropics and cognitive enhancers. I am thinking to combine both with magnesium, and after a while slowly let Lithium Oratate go. Thanks for your time to reply. I think I have developed OCD and ADHD. Rafik Karaman. MDMA decreasing GSH is not evidence that 5-HT2A activation decreases GSH for example. 3 days ago I started taking Ashwagandha and stopped taking Lithium Oratate. That is something which has been claimed in numerous reviews, like this one on Reddit : “It was a great mood stabilizer for me as someone who has mood swings and lack of impulse control. She went to the emergency department with nausea and was discharged after a few hours to a psychiatric hospital. Does lithium orotate make you tired? Lithium Orotate is great if you are ADHD because lithium calms the hyperactivity in your brain. Lithium calms you by decreasing sensitivity of post-synaptic norepinephrine receptors. Meaning the atmosphere and circumstances you take them in .... Dictates the experience you have and the way the effect your brain chemistry. Press question mark to learn the rest of the keyboard shortcuts, https://www.ncbi.nlm.nih.gov/pubmed/17572501. No need to quit taking it. So my question is really simple, Lithium orotate and pregnenolone are not sold over the counter in Canada but they seem to be easy to order from many US online sellers. Available in dietary supplement form, lithium orotate is touted as a natural treatment for a wide range of mental health problems. Lithium orotate is a much lower dose of lithium than prescription lithium but is taken as a supplement to help alleviate ADHD and depressive symptoms. Press J to jump to the feed. In the pre-marketing pooled 8-week placebo-controlled researches in clients with MDD, 1, 834 individuals were exposed to Pristiq (50 to 400 milligrams). I read that flax seed oil and vitamin C can help with negative effects and avoid IB Profen if you take it regularly. Lithium orotate is one of several supplements which can support and assist the body to work around this mutation. Ever since I abused countless drugs like benzodiazepines, LSD, psilocybin, Amphetamines, Cannabis, Etc. I’m confused about a lot of this. Exact same substance .... Having polar opposite effects. This suggests that Lithium, at a low dosage, has a beneficial effect on behavior. Cannabis through constant activation of the CB2 cannabinoid receptor. Please do not use it daily without medical supervision. And I do wanna mention again the fact that LSD is my last drug of choice for the reasons mentioned above, relating to the activation of 5HT2A receptors such as, vasoconstriction, anxiety, OCD , depression, fatigue, insomnia, sexual problems, etc. Press J to jump to the feed. Lithium orotate ADHD. Lithium orotate weight loss So far this is working Ok in that her outbursts are shorter than they used to be. So glad things are getting better. 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